MLB Division Series Preview and Betting Odds

Last Updated on October 6, 2025 10:30 am by Erwin Noguera

The MLB is heating up as we move past the regular season. We are now heading into the second and third games of the Division Series, with eight teams eager to compete for a chance to become the League Champions.

The American League goes down to the Blue Jays, who are currently facing the Yankees in an all-out ALE Series, while the Tigers and the Mariners fight their own to see who comes out on top.

In the National League, our contenders are the Phillies, who are facing off against the Los Angeles Dodgers, while the Brewers and the Cubs have an ALC clash as they see who makes it into the last match before the World Series.

The National League teams are playing their second match in the series today. Meanwhile, the American League side will enter the third match tomorrow, making things quite interesting as we approach the midpoint.

At Gambyl Exchange, you can explore all the predictions for the MLB, the final bets for this Matchday, and the odds for each match.

MLB Division Series: Phillies vs. Dodgers

The LA Dodgers took some ground by winning the first clash at the Phillies’ home stadium, and are now eager to try and make the most of it in the second clash.

The first clash earned them a 5-3 win, so the Phillies are going to be looking to get the upset on this second match and even things out before they are against the fence on this 5 match series.

For the Dodgers, it is up to Blake Snell to make up for the time he missed due to injury, but he has kept up to expectations lately, which means that the Phillies will have to work their way to get a needed victory.

The left-handed Jesus Luzardo will be the opening pitcher for the Phillies, and we believe that he will showcase in this match and give the home team the breathing room they need before they enter the middle point of the series.

Phillies vs. Dodgers Betting Pick: Phillies

MLB Division Series: Brewers vs. Cubs

The Brewers are performing well in this series, having won the first game as hosts. They aim to extend their lead before the dynamics shift, working to remain as comfortable as possible entering the third match.

One concern is that the Milwaukee lineup has to contend with Jackson Chaurio’s late-game hamstring injury, which may result in Isaac Collins starting in left field.

This matchup will be a strategic battle, as the Cubs have chosen the left-handed pitcher Shota Imanaga as their starter for Game 2.

We believe the Brewers will win this game, gaining the confidence boost they need for a quick series victory and a few days of rest.

Brewers vs. Cubs Betting Pick: Brewers

MLB Division Series: Tigers vs. Mariners

This matchup has everyone wondering about the outcome, as both the Tigers and Mariners have each won a game in this series so far. The fact that the Mariners managed to even things up in the second game shows their improvement.

The competition has been quite intriguing; the first game ended with a score of 3-2 in favor of the Tigers, while the second game saw the Mariners triumph by the same score.

We hope to see this exciting trend continue, as we would love to witness four thrilling clashes before the series potentially goes to a tiebreaker in the fifth and final game. However, we believe the Mariners will take the lead in this third game.

Tigers vs. Mariners Betting Pick: Mariners

MLB Division Series: Yankees vs. Blue Jays

The Yankees will be hosting this matchup and will need to put forth their best effort, as the Blue Jays have established a strong lead with two victories in their home games.We can expect this game to be action-packed.

After the last match ended with a score of 13-7 in favor of the Blue Jays, they will be eager to take the field again and secure one more victory to finish the series early. However, the Yankees will be counting on the support of their home crowd to provide a much-needed confidence boost.

While many are leaning towards the Yankees as favorites to stage a comeback in the series, there are reasons to believe that the Blue Jays are likely to complete a three-game sweep.

Yankees vs. Blue Jays Betting Pick: Blue Jays