Last Updated on July 9, 2025 12:16 pm by Erwin Noguera
This weekend, the MLS brings us a battle between Cincinnati and Columbus Crew, with both teams searching for the Conference lead.
In the East, FC Cincinnati has managed to climb to the top thanks to its consistency, but the competition does not let up. Nashville and Philadelphia are close behind, determined to take advantage of any slip-up by the leaders.
Meanwhile, in the Western Conference, the situation is even tighter. San Diego FC continues to lead, but with a lead that has already been reduced to just one point over the Whitecaps. The worrying thing for the California side is that the Canadians still have a game in hand, which could give them the lead in the short term if they keep up their competitive pace.
At Gambyl Exchange, you can explore all the predictions for the MLS, the final bets for this Matchday, and the odds for each match.
Cincinnati vs. Columbus Betting Odds and Info
Cincinnati +110 | Columbus SC +218 | Draw Offs: +298 |
When? | Saturday, September 22 at 8:30 PM ET, 7:30 PM CST, 6:30 PM MT, and 5:30 PM PT |
Where? | TQL Stadium. |
Where Can I Watch It? | Apple TV |
Why Bet on Cincinnati?
FC Cincinnati firmly leads the Eastern Conference, boasting a record of 13 wins, three draws, and five losses, with a balance of 33 goals for and 27 against.
Although they are in a privileged position, the statistics reveal a defensive issue that must be addressed if they want to progress in the standings.
They come into matchday 22 on the back of a 2-1 win over Chicago Fire, with goals from Evander and Kevin Denkey. However, their opponents reduced the deficit in the second half, again exposing a defense that still struggles and concedes too easily.
Coach Pat Noonan acknowledged that, although the team “defended strongly” to sustain the win, there is still room to strengthen the backline.
Against this backdrop, their next challenge will be to find a balance that allows them not only to lead but to do so with greater solidity.
Why Bet on the Columbus Crew?
Columbus Crew, on the other hand, is also consolidated at the top. They have accumulated 10 wins, eight draws, and only three defeats, totaling 38 points in 21 games, just four fewer than Cincinnati. Their season has been solid, and their recent form is impeccable: they are unbeaten in four games, including a 1-1 draw away to Seattle Sounders.
In the previous match, Columbus took on the Sounders at Lumen Field and drew 1-1, with goals from Diego Rossi for the visitors and Paul Rothrock for the home side, in a match marked by a serious injury to goalkeeper Stefan Frei.
Final Betting Analysis: Cincinnati vs. Columbus
In the last 10 games played between these two teams, Columbus has dominated the series with four wins. Cincinnati, on the other hand, has accumulated two wins, while four games have ended with a tie on the scoreboard.
In addition, the last two games played between them ended in a draw.
At Gambyl Exchange, we can see that there is a Moneyline that favors FC Cincinnati at +110, while Nashville SC starts at +218.
That said, we expect parity to continue and the match to end with a draw on the scoreboard.
Look for a Draw. If you put $100 on a Draw at +298, you’ll see a $298 win with a total payout of $398.