Last Updated on September 25, 2025 11:49 am by Erwin Noguera
Matchday 33 marks the start of the decisive phase of the MLS regular season, with several teams focused on securing a playoff spot or improving their position in the race for the Supporters’ Shield. At this stage, every game is crucial, and teams are looking to finish strong before entering the final stretch of the tournament. The picture is tight, and any points won or lost can change the course of the standings.
In the Eastern Conference, Philadelphia Union remains at the top with a significant lead, although FC Cincinnati and Charlotte FC are still close behind, showing that the fight for the top spot is not yet decided. On the other side, San Diego FC holds first place in the West, boosted by its strength at home, while Vancouver Whitecaps and Minnesota United are hot on its heels and continue to apply pressure at the top.
For teams hovering around mid-table or lagging, this matchday is vital if they are to keep their hopes alive. At this stage, the margins for error are minimal: the ability to pick up points away from home or take advantage of home advantage could mean the difference between dreaming of the playoffs or saying goodbye early. Matchday 33 is shaping up to be a weekend full of drama, where strategy and mentality will weigh as heavily as footballing quality.
At Gambyl Exchange, you can explore all the predictions for the MLS, the final bets for this matchday, and the odds for each match.
MLS Weekly Picks Betting Odds
New England +100 |