Chargers vs. Raiders Betting Odds and Free Pick

Last Updated on November 28, 2025 12:12 pm by Erwin Noguera

The Chargers face the Raiders in an AFC West battle loaded with division pride, playoff implications, and the chance for a momentum swing heading down the stretch.

This rivalry game could redefine each team’s trajectory: the Chargers aim to assert control with a sharp defense and efficient offense. At the same time, the Raiders look to disrupt and prove they still matter in a crowded division.

The Chargers also enter fresh from a bye week, giving them time to regroup after a tough loss and fine-tune their plans.

For Las Vegas, this marks another opportunity to salvage a disappointing season and show resilience despite recent struggles.

At Gambyl Exchange, you can explore all the predictions for the NFL, the final bets for this Matchday, and the odds for each match.

Chargers vs. Raiders Betting Odds and Info

Why Bet on the Chargers?

The Chargers enter this week with a 7-4 record, but also with the urgency to erase the painful 35-6 beating they suffered against Jacksonville. That loss exposed several concerns that Los Angeles cannot afford to carry into such an important divisional matchup.

If they want to get back on track, they need to rediscover the dominant form they showed at the start of the year, the form that made them look like a serious threat in the conference. The Raiders’ defense has been one of the least reliable in the league, so the stage is set for the Los Angeles offense to once again be aggressive and efficient in the red zone.

The big question mark is the availability of Hampton, whose activation window recently opened, but his return is still not assured after the ankle injury that has sidelined him since Week 5. If he sees action, his presence would completely change the offensive dynamic, as his explosiveness and ability to punish defenses made him a key player in September.

Even so, Kimani Vidal has responded solidly in his absence and would continue to play a prominent role. If the Chargers manage to establish the ground attack and free up Hampton (or Vidal) in the open field, they should be on track for a much-needed win that would take them to 8-4 and keep them firmly in the AFC race.

Why Bet on the Raiders?

On the other side of the field, the Raiders arrive with a season that has completely derailed. Their 2-9 record reflects a dangerous combination of mistakes, poor execution, and close games that have slipped through their fingers. After a promising victory over Tennessee in Week 6, Las Vegas fell into a five-game losing streak.

Most strikingly, three of those losses were by narrow margins against playoff-caliber opponents (the Bears, Broncos, and Jaguars), showing that the team can compete but doesn’t know how to close out games. The precedent between the two teams also plays a role: in Week 2, the Chargers had already beaten them 20-9 with a problematic performance by Geno Smith, who threw three interceptions.

The most puzzling point remains the management of offensive talent, especially in the case of Ashton Jeanty, who arrived with expectations of being the engine of the attack. Although his production is not bad (604 rushing yards, plus 37 receptions for 221 yards and four touchdowns), his usage has been inconsistent and far from what many anticipated.

Despite this, Jeanty has been a real threat in the red zone and has eight total touchdowns, a sign that when he is involved, he produces. To have a chance this Sunday, the Raiders must protect the ball for Smith, rely on Jeanty in long sequences, and find ways for the offense to sustain drives. Otherwise, the game could slip away from them as quickly as their last few matchups.

Final Betting Analysis: Chargers vs. Raiders

This is a great rivalry in league history, with 132 games played between the two teams. During this time, Las Vegas has dominated the series with 69 wins, the Chargers have accumulated 61 wins, and one game has ended in a tie.

As we mentioned, the most recent game between them, on September 15, 2025, ended in a resounding 20-9 victory for the Chargers.

At Gambyl Exchange, we can see that there is a Moneyline that favors the Chargers at -588, while the Raiders start at +391.

For this game, we predict a Chargers victory.

Look for a win on the Chargers. For example, if you put $100 on the Chargers at -588, you’ll see a $17.01 success with a total payout of $117.01.

Chargers vs. Raiders Betting Pick: Chargers