Lions vs. Packers for TNF Betting Odds and Free Pick

Last Updated on November 25, 2025 1:01 pm by Erwin Noguera

The Lions meet the Packers on Thursday Night Football in a fierce NFC North clash loaded with rivalry energy, playoff implications, and high-stakes momentum.

With the season entering its final stretch, every play weighs like a final, and every team knows that a misstep could cost them a ticket to the playoffs. The table is set: strong emotions, packed stadiums, and millions of fans around the world ready for another unforgettable edition of this sporting holiday.

Few games encapsulate the essence of Thanksgiving Day as much as this divisional matchup. Detroit, the traditional host of the holiday, enters its 86th Thanksgiving game with the obligation to respond to a relentless schedule that has tested them week after week.

After alternating wins and losses since their bye week, the Lions face a decisive stretch that includes consecutive games against direct rivals: the Vikings, Commanders, Eagles, Giants, Packers, Cowboys, and Rams. The stakes are high, and this matchup with Green Bay could be a turning point for their season.

At Gambyl Exchange, you can explore all the predictions for the NFL, the final bets for this Matchday, and the odds for each match.

Lions vs. Packers Betting Odds and Info

Why Bet on the Lions?

Detroit has the advantage of accumulated experience in this setting, something few franchises can boast. No team has been part of Thanksgiving Day as many times as the Lions, with 85 appearances that translate into a historic record of 38-45-2, reflecting decades of tradition and consistency.

That familiarity with the unique atmosphere of this day often makes a difference, especially when the rest of the league is watching. Although they have gone through difficult times in recent years (including that prolonged drought between 2017 and 2023, which left its mark on the fans), last year’s victory provided a moral boost and a reminder that Detroit can indeed raise its level under the holiday spotlight.

That result revitalized internal confidence, reinforced the coaching staff’s message, and made it clear that, in games fraught with media pressure, the Lions remain a rival capable of surprising and competing on equal terms.

Why Bet on the Packers?

On the other hand, Green Bay also carries on a deep-rooted Thanksgiving tradition, a story that is part of the franchise’s DNA.

For more than a decade, the Packers and Lions faced off year after year on this special date, making this matchup one of the most recognized rituals on the NFL calendar. Over time, their presence on this holiday regained momentum, and today they have made 38 appearances on Thanksgiving, backed by a record of 16-20-2, a figure that reflects both their dominant eras and their rebuilding phases.

The momentum they bring with them is no coincidence. Green Bay has been able to respond when the whole country is watching, and their recent performances on this stage prove it. In 2023, they surprised Detroit with a victory at Ford Field, a result that marked a turning point in the recent rivalry.

A year earlier, they had put in another solid performance with a clear win over Miami in prime time, reinforcing the idea that this team tends to rise to the occasion when playing in the spotlight on a national holiday. All of this fuels the mood in the locker room: the Packers travel with the confidence of knowing that they have already proven their ability to shine on Thanksgiving and that they can do it again.

Final Betting Analysis: Lions vs. Packers

Detroit is looking for revenge after the blow they received in Week 1, when the Packers dominated them without mercy. Green Bay, for its part, knows that another victory would not only consolidate its position in the division but also put it one step away from reclaiming the historic top spot in this festive rivalry. Tradition, rivalry, and a northern classic with a lot at stake.

At Gambyl Exchange, we can see that there is a Moneyline that favors the Lions at -169, while the Packers start at +290.

For this game, our prediction is a victory for the Lions.

Look for a win on the Lions. For example, if you put $100 on the Lions at -169, you’ll see a $59.17 success with a total payout of $159.17.

Lions vs. Packers Betting Pick: Lions