Last Updated on September 19, 2025 1:37 pm by Erwin Noguera
Two teams loaded with talent and legitimate Super Bowl aspirations will headline the best matchup of Week 3 in the NFL, as the Baltimore Ravens take on the Detroit Lions on Monday Night Football.
The Ravens bounced back from a season-opening loss by defeating the Cleveland Browns 41-17, on a fantastic night for quarterback Lamar Jackson, who threw for 222 yards and four touchdowns.
The Lions also failed to start with a win, but last week they crushed the Chicago Bears 52-21, led by a standout performance from Jared Goff, who finished with 334 yards and five touchdown passes.
At Gambyl Exchange, you can explore all the predictions for the NFL, the final bets for this Matchday, and the odds for each match.
Baltimore Ravens vs. Detroit Lions Betting Odds and Info
When? | Monday, September 22, 8:15 pm ET, 7:15 pm CST, 6:15 pm MT, and 5:15 pm PT |
Where? | M&T Bank Stadium |
What are the Odds for the Ravens? | -125 |
What are the Odds for the Lions? | -111 |
What is the Over/Under? | 49.5 |
Where Can I Watch it? | NFL Network |
Why Bet on Ravens?
The NFL season began with the Baltimore Ravens as the top Super Bowl contender according to most experts, but they had a tough start against the Buffalo Bills.
In that opener, they lost 41-40, but in their second outing, they bounced back with a 41-17 win on a fantastic night from Lamar Jackson.
The quarterback finished 19 of 29 passing for 225 yards and four touchdowns. To add to that, he contributed 13 yards on two carries.
It’s clear that the talent of the two-time MVP sets the tone for this team, which saw two touchdowns from Devontez Walker and one each from DeAndre Hopkins and Tylan Wallace.
Experts expect Baltimore to capitalize on the great talent on its roster and start stacking wins. Many even have them as the favorite to win the AFC.
Last season, the Ravens already put together a strong campaign with 12 wins and five losses. However, the Bills proved to be their nightmare, knocking them out in the divisional round.
Baltimore is unbeaten in its last four home games, with the last loss coming on December 1 against the Eagles. In addition, they have only lost once in their history to the Lions.
Why Bet on Lions?
Just like the Ravens, the Detroit Lions are contenders to reach the Super Bowl this year, after coming very close last season. They kept a competitive roster and have shown signs of having a great offense.
In their first game, their offense wasn’t sharp, and they lost 27-13 to the Green Bay Packers, but they bounced back against the Chicago Bears with a 51-21 win.
It was an outstanding performance from quarterback Jared Goff, who went 23-for-28 with 334 passing yards and five touchdown passes. He wasn’t intercepted once.
Jared is one of the best in his position in the league, and he proved it in this game. Credit also goes to Jahmyr Gibbs with his 12 carries and Amon-Ra St. Brown, who had nine receptions for 115 yards and three touchdowns.
However, Detroit lost two key figures who helped them succeed last season—head coach Ben Johnson and defensive coordinator Aaron Glenn—which could put their supremacy in the NFC North at risk.
Both the Packers and the Bears scored more than 20 points against them, which may signal a drop in their defensive performance.
Final Betting Analysis: Ravens vs. Lions
The Baltimore Ravens and the Detroit Lions are both expected to contend for the Super Bowl. However, the victory should go to the visiting team, as their offense is more decisive and their defense should be performing at a high level.
The numbers at Gambyl Exchange have the Lions listed as the favorite, as the moneyline for them shows -111; meanwhile, the Ravens have odds of -125.
History shows that the Ravens have won six of seven meetings against the Lions, and at home, they have a record of 4-0. The most recent matchup ended in a 38-6 win for Baltimore.
Go for a straight win for the Lions in the Moneyline. If you bet $100 at -111, you will gain $90 for a total payout of $190.