Serie A Matchday 24 Betting Favorites

Last Updated on February 4, 2026 1:28 pm by Erwin Noguera

Matchday 24 of the Serie A shapes up as one of the most attractive rounds on the calendar, with decisive games in the race for the title and the European qualification spots. At this stage of the season, every point carries significant weight and margins for error are slimmer than ever.

Inter, the solid league leaders, will look to extend their dominance and take another firm step toward the Scudetto when they visit Sassuolo.

Napoli, currently third in the standings, travels to face Genoa, while Juventus—firmly in the Champions League qualification zone—enters Matchday 24 aiming to reaffirm their strong form at home against Lazio.

Finally, fifth-place Roma hosts Cagliari at the Stadio Olimpico, meanwhile, Milan vs. Como game has been postponed due to the Winter Olympic Games that this weekend will have the inauguration in Milano.

At Gambyl Exchange, you can explore all the predictions for the Italian Serie A, the final bets for this matchday, and the odds for each match.

Serie A Weekly Pick Betting Odds

Serie A Matchday 24: Genoa vs. Napoli

Daniele De Rossi’s Genoa saw their five-match unbeaten run come to an end, a stretch in which they had only won two matches, both at home. They lost last weekend to Lazio 3–2 after conceding a penalty in the final play, dropping to 14th place with 23 points, six above the relegation zone. At home, they have two consecutive victories, scoring three goals in each, and are unbeaten in their last three matches.

Napoli comes into this match with a clear need to win. The reigning Italian champions have endured an up-and-down campaign, but arrive after beating Fiorentina following their Champions League elimination and are eager to stay competitive in Serie A. However, Napoli will be without De Bruyne, Anguissa, Politano, Milinković-Savić, Neres, and Mazzocchi. Romelu Lukaku has seen limited minutes this season, and against Fiorentina, they also lost their captain, Giovanni Di Lorenzo, to injury.

Genoa vs. Napoli Betting Pick: Napoli

Serie A Matchday 24: Sassuolo vs. Inter

Sassuolo are floundering in mid-table. With 29 points, they sit 11th after eight wins, five draws, and 10 losses, scoring 27 goals and conceding 29. They are on the rise, as after seven matches without a win and three straight defeats, they have now recorded back-to-back victories, the most recent coming away at Pisa (1–2).

Inter heads into their matchup against Sassuolo aiming to consolidate their position at the top of the table and stay firmly on track in the Scudetto race. The ‘Nerazzurri’ have enjoyed a very solid league campaign, leading the standings with 55 points. They are coming off a 0-2 win over Cremonese and have 11 unbeaten games in Serie A, winning 10 of them. Lautaro Martínez tiene tres partidos por liga marcando y es el goleador del torneo con 13.

Sassuolo vs. Inter Betting Pick: Inter

Serie A Matchday 24: Juventus vs. Lazio

Juventus arrive in strong form, backed by a positive run in the league and impressive defensive solidity. Since Luciano Spalletti’s arrival, Juventus have been the best defensive team in the league, conceding just two goals in the last seven games, including two in the Champions League. Offensively, they have scored 15 goals in their last five Serie A matches, with Kenan Yıldız and Jonathan David leading the charge. They arrived at this game with two huge victories against Napoli (3-0) and Parma (1-4)

Lazio, meanwhile, faces a demanding test away from home. The Rome-based side has been inconsistent throughout the season, alternating strong performanceswith unexpected setbacks. They have just two victories in their last eight matches, one of them the past weekend against Genoa with a last-minute penalty goal from Danilo Cataldi (3-2).

Juventus vs. Lazio Betting Pick: Juventus

Serie A Matchday 24: Roma vs. Cagliari

Roma welcomes Cagliari to the Stadio Olimpico with a clear objective: secure all three points to stay firmly in the race for European qualification. The ‘Lupa’ come into the match with better overall sensations, particularly at home, where they have just one loss in their last seven games, winning five of them. However, the ‘Giallorossi’ are coming off a 1–0 defeat to Udinese on Matchday 23, losingfourth place.

Cagliari, on the other hand, approaches the game from a more precarious position, focused primarily on collecting points to move away from the relegation zone. They are in great form, winning their last three games, the last with a trashing 4-0 against Verona, moving 12th with 28 points.

Roma vs. Cagliari Betting Pick: Roma