Previsão e probabilidades de apostas para Denver x San Francisco

Last Updated on Agosto 6, 2025 9:27 am by Erwin Noguera

The 2025 NFL preseason continues with a marquee showdown between the Denver Broncos and the San Francisco 49ers, taking place at Levi’s Stadium in Santa Clara, California. It’s not just a preseason opener—it’s the culmination of joint practices between the two teams and a crucial early test for young players and starters looking to build chemistry ahead of Week 1.

Denver is coming off a successful season with rookie quarterback Bo Nix leading the charge. San Francisco heads into the game with their core intact but is focused on integrating new contributors while preserving the health of their key players.

Denver Broncos vs. San Francisco 49ers Betting Odds and Info

Por que apostar no Denver Broncos?

The Broncos enter their preseason opener with the majority of starters expected to play, per head coach Sean Payton—a deliberate shift to give fans and evaluators a true look at the team’s identity. Most importantly, Bo Nix, who earned widespread praise during his rookie season, is anticipated to take the field.

In 2024, Nix threw for 3,775 yards and 29 touchdowns, rushed for 430 yards and four more scores, and finished near the top in Offensive Rookie of the Year voting. Despite playing through three transverse process fractures late in the season, Nix’s resilience stood out.

Nix has already become a franchise cornerstone. Payton predicts the second-year QB will rank among the NFL’s top signal-callers within two years—a bold forecast supported by his rookie-level output and leadership impact. In Santa Clara, Nix will be flanked by weapons like Courtland Sutton, receiver Marvin Mims Jr., and tight end Greg Dulcich, all of whom are expected to have meaningful roles in Payton’s pro-style scheme.

Behind Nix, the competition for the backup role is intense. Sam Ehlinger has drawn positive attention after displaying poise and efficiency in joint practices, while veteran Jarrett Stidham provides experience in the QB room. The offensive line appears more stable this season, with Ben Powers and Lloyd Cushenberry III anchoring the interior, and depth being tested by recent additions like former Nebraska tackle Turner Corcoran.

On defense, the Broncos are reshaping their rotation. Rookie edge rusher Jonah Elliss and cornerback Riley Moss are expected to log significant snaps, as Payton demands increased physicality from the second unit. The addition of former 49er Talanoa Hufanga brings veteran leadership to a secondary looking sharper after a disappointing 2024 run in run defense.

With playoff aspirations renewed and roster battles hotly contested, this game offers a chance to show progress and evaluate key contributors—especially at quarterback and on defense.

Por que apostar no San Francisco 49ers?

For the 49ers, the preseason opener is about evaluating depth rather than showcasing stars. Head coach Kyle Shanahan has already confirmed that core players such as Brock Purdy, Christian McCaffrey, and Fred Warner will not play in this matchup. Instead, San Francisco will use the game to assess its backups and developmental players ahead of the regular season.

In the quarterback room, attention turns to Brandon Allen and rookie Carter Bradley, who will receive most of the playing time behind Purdy. Allen has shown reliability in camp, but Bradley will have his first live test against an NFL defesa.

Defensively, the 49ers will evaluate second-string edge weapons and secondary depth. With stars like Nick Bosa and Fred Warner sitting out, young players such as Robert Beal Jr., Bradlee Anae, and safeties like Ji’Ayir Brown have the chance to stake their claim. San Francisco also continues to assess kicker Jake Moody, whose preseason performance will be vital given his inconsistency last year.

The coaching staff aims to see how the next wave of contributors performs in live-game situations. After narrowly missing the playoffs, San Francisco knows its depth will determine how long it stays in contention—making this preseason matchup more than just a dress rehearsal.

Final Betting Analysis: Denver vs. San Francisco

Based on what both coaches have said this week, the Denver Broncos hold the advantage and come in as favorites, especially since they’ll be using several starters, including quarterback Bo Nix. Because of that, we believe Denver will come out with the win.

Os números em Troca de Gambila reflect that favoritism, with Denver listed at -278 on the Moneyline, while San Francisco sits at +210.

The last time these teams faced off was two years ago in a preseason game, where the 49ers won 21–20. Meanwhile, their most recent regular-season meeting was on September 25, 2022, a tight matchup that Denver won 11–10.

Go for a win for Denver. If you bet $100 at -260, you will gain $38 for a total payout of $138.

Denver Broncos vs. San Francisco 49ers Betting Pick: Denver