Serie A Matchday 38 Betting Favorites

We have reached the final matchday of Serie A, matchday 38, and it’s a big one. The title, spots for three international competitions, and two relegation positions are all at stake.

At the top, Napoli leads by just one point over Inter. Napoli will host Cagliari, while Inter will be on the road against Como.

For the international cup spots, Juventus is aiming to return to the Champions League and must beat Venezia away, a team also fighting to avoid relegation.

Roma and Lazio are just a few points behind and still have a chance at a Champions League spot. To get it, they need Juventus to lose and must beat Torino and Lecce, respectively.

At Gambyl Exchange, you can explore all the predictions for the Italian Serie A, the final bets for this Matchday, and the odds for each match.

Serie A Weekly Picks Betting Odds

Serie A Matchday 38: Como vs. Inter

Como has had a fantastic season upon their return to the top flight after more than 20 years, with Cesc Fàbregas quickly becoming one of the most sought-after coaches. They’re sitting in 10th place with 49 points and are on an eight-game unbeaten run—drawing the first and last matches of that stretch and winning the six in between.

Inter missed a crucial opportunity last weekend, drawing 2-2 at home against Lazio and conceding a goal in the 90th minute while keeping an eye on the Champions League final. They failed to capitalize on Napoli’s draw and now sit one point behind, meaning they must win and hope Napoli doesn’t. Lautaro Martínez and Davide Frattesi missed the last match due to injury but are expected to return this Friday.

Como vs. Inter Betting Pick: Inter

Serie A Matchday 38: Napoli vs. Cagliari

Napoli was fortunate that Inter failed to capitalize, as they have drawn their last two matches—first a 2-2 at home against Genoa, and then a 0-0 versus relegation-threatened Parma. They hold a one-point lead over the Milan side and are unbeaten in 11 matches, though only six were wins. With just 27 goals conceded, they have the best defense in the league.

Cagliari secured a crucial 3-0 win over Venezia last weekend, which guaranteed their stay in the top flight. Davide Nicola’s team heads into the match against the league leaders with peace of mind, having accomplished their main objective. However, their away form has been poor throughout the season, managing just six points from the last 27 available on the road.

Napoli vs. Cagliari Betting Pick: Napoli

Serie A Matchday 38: Venezia vs. Juventus

Venezia has it very tough. With 29 points, they sit in 19th place, and if they want to stay in Serie A, they must win this weekend and hope both Lecce and Empoli lose. There’s still hope, especially since in their last home match they beat Fiorentina 2-1, and earlier this season they managed a draw against Juve in Turin.

Juventus heads into this final matchday with everything in their favor. With 67 points, they only need a win to secure fourth place and a Champions League spot. They’re coming off a 2-0 victory over Udinese, but their recent away form hasn’t been great—three draws and two losses in their last five road games—results that won’t be enough this time.

Venezia vs. Juventus Betting Pick: Juventus

Serie A Matchday 38: Lazio vs. Lecce

Lazio and Pedro added more drama to Serie A. The Spaniard scored a brace against Inter, with the second goal coming in the 90th minute to secure a draw for his team, and in Naples, he’s already being hailed as a saint. Lazio currently sits on 65 points, holding a spot in the Conference League. Roma is fifth with 66, and Juventus is fourth with 67, so Lazio is hoping for a slip-up from either to qualify for a higher competition. But beware—a loss combined with a Fiorentina win could leave them out of Europe entirely. They are undefeated in eight games but have won only three in that span and tied the last two.

Lecce is fighting for its life. With 31 points, they currently sit in 17th place, narrowly avoiding relegation. A loss, combined with either a draw from Empoli or a win from Venezia, would result in their demotion to Serie B.

They had gone 13 matches without a win, including eight losses, but finally broke the streak last weekend with a 1-0 victory over Torino.

Lazio vs. Lecce Betting Pick: Lazio