Bills vs. Chiefs Free Pick and Betting Odds

Last Updated on octubre 31, 2025 12:36 pm by Erwin Noguera

In one of the most intriguing matchups of Week 10 in the NFL, the Buffalo Bills will host the Kansas City Chiefs in a crucial game for both teams’ playoff hopes, featuring a marquee showdown between two of the league’s best quarterbacks.

The Bills bounced back from a pair of losses in dominant fashion, crushing the Carolina Panthers 40-9.

As for the Chiefs, they’re in great form and are coming off a 28-7 win over the Washington Commanders.

En Gambyl Exchange, puedes explorar todas las predicciones para la NFL, the final bets for this Matchday, and the odds for each match. We also offer special odds for the game featuring the Buffalo Bills vs. Pittsburgh Steelers vs. Fabi, where you can place your bet, and we will match the same amount.

Buffalo Bills vs. Kansas City Chiefs Betting Odds and Info

Why Bet on Bills?

A couple of bad weeks have hurt the Buffalo Bills in the AFC East. After two straight losses, their record stands at 5-2, dropping them to second place in the division behind the New England Patriots, who sit at 6-2 but have played one more game.

The Bills started the season 4-0 but then fell to the Patriots and Falcons in back-to-back games. After a bye week, they returned to action last Sunday with a dominant 9-40 win over the Carolina Panthers.

It wasn’t a demanding game for Josh Allen through the air—he completed 12 of 19 passes for 163 yards and a touchdown, caught by Khalil Shakir.

Most of the action came on the ground, where both Allen and James Cook scored two rushing touchdowns each. Cook had 19 carries for 216 yards, becoming just the fourth player in NFL history to record over 215 yards and two or more touchdowns on fewer than 20 carries.

Cook currently leads the NFL in rushing yards per game (107.6) and yards per carry (6), ranks second in total rushing yards (753), and fourth in touchdowns (7).

Right now, Allen and Cook form one of the league’s most dangerous duos, and with the quarterback on the verge of breaking several records, doing so against the Chiefs would make it even more special.

One concern, however, is the defense; with several injuries piling up, the Bills can’t afford any lapses against a team like Kansas City.

¿Por qué apostar por los Chiefs?

The Kansas City Chiefs started the season on the wrong foot with two straight losses, but then got back on track with five wins in six games, proving they’re still strong title contenders. Their 5-3 record places them third in the AFC West and seventh in the conference.

They’re currently on a three-game winning streak, the latest being a 28-7 Monday night victory over the Washington Commanders. It was a great performance from Patrick Mahomes, who completed 25 of 34 passes for 299 yards and three touchdowns. The downside was that he threw two interceptions, something that hadn’t happened since the last Super Bowl, bringing his total to four this season.

The touchdowns came from Rashee Rice, Travis Kelce, and Kareem Hunt through the air, with Hunt also adding one on the ground. The running back will be a key piece in the coming weeks following Isiah Pacheco’s injury, which will sideline him for several games.

On defense, Michael Danna and Jack Cochrane both intercepted Marcus Mariota, marking the first interceptions of their NFL careers.

The Chiefs are tied with the Cowboys and Rams for the most touchdowns this season (17) and rank fourth in passing yards (2,099).

Análisis final de apuestas: Bills vs Chiefs

It’s set to be a great and very evenly matched game between two top teams and two elite quarterbacks. We believe the Bills have a slight edge playing at home, and after Cook’s outstanding performance, the running back will be key to securing the win.

Los numeros en Gambyl Exchange have the Chiefs as the favorite, with their Moneyline at -130, while the Bills are listed at +110.

The last time these two teams faced each other was on January 26 of this year, in the conference final, where the Chiefs won 32-29. Their most recent regular-season meeting was on November 17, 2024, in Buffalo, where the home team won 30-21. The Bills have won the last four regular-season meetings between them.

Go for a win for the Bills. If you bet $100 at +110, you will gain $110 for a total payout of $210.

Bills vs. Chiefs Betting Pick: Bills