Los Angeles Rams Betting Odds

Last Updated on October 21, 2025 6:26 am by Henry

Team Overview

The Rams won the NFC West in 2024 and remain contenders in 2025. Matthew Stafford’s health will determine their ceiling, but offseason moves, including adding Davante Adams, give Sean McVay’s offense firepower.

Offensive Line Analysis

The Rams kept stability by re-signing Coleman Shelton. Protection is solid but lacks elite depth.

Defensive Line Analysis

The Rams invested in depth, bringing in Poona Ford. The unit looks young and energetic, though secondary support could be a weakness.

Week 1 – vs. San Francisco 49ers

Result & Key Stats
The Seattle Seahawks dropped their opener 17–21 at home. QB Geno Smith threw for 198 yards and 1 TD but struggled with third-down consistency. WR Jaxon Smith-Njigba paced the offense with 7 catches for 89 yards.

Key Moments & Injuries
Seattle’s defense generated two interceptions, including one by CB Riq Woolen, but the offense failed to capitalize. Missed tackles late in the fourth quarter paved the way for the missing go-ahead drive. Rookie DE Byron Murphy II exited briefly with cramps but returned to action.

Looking Ahead
The Seahawks host the Arizona Cardinals in Week 2. Improving third-down efficiency and wrapping up tackles will be essential keys to a rebound.

Week 2 – vs. Tennessee Titans

Result & Key Stats
The Los Angeles Rams fell 23–20 in overtime at Tennessee. QB Matthew Stafford threw for 279 yards and 1 TD, while WR Puka Nacua recorded 8 receptions for 104 yards.

Key Moments & Injuries
Tennessee sealed the win with a late FG after stuffing the Rams on 4th down. LB Ernest Jones led the defense with 11 tackles. Rookie G Jonah Jackson missed the game with an ankle injury.

Looking Ahead
The Los Angeles Rams travel to play the Eagles in Week 3.

Week 3 – vs. Philadelphia Eagles

Result & Key Stats
The Los Angeles Rams fell 33–26 after blowing a 19-point lead at SoFi Stadium. QB Matthew Stafford threw for 278 yards and 1 TD, while WR Puka Nacua posted 108 yards on 7 receptions.

Key Moments & Injuries
The Rams led 26–7 in the first half, but costly mistakes and protection breakdowns let Philadelphia storm back. LB Ernest Jones led the defense with 11 tackles. No major new injuries were reported, but the O-line remains thin.

Looking Ahead
The Los Angeles Rams visit the Colts in Week 4, needing sharper pass protection and late-game execution to rebound.

Week 4 – vs. Indianapolis Colts

Result & Key Stats
The Los Angeles Rams earned a 27–20 win at home, improving to 3–1. QB Matthew Stafford threw for 276 yards and 2 TDs. WR Puka Nacua had 7 catches for 98 yards.

Key Moments & Injuries
Stafford connected with WR Cooper Kupp for a red-zone TD, and LB Ernest Jones led the defense with 9 tackles.

Looking Ahead
The Rams host the San Francisco 49ers in Week 5.

Week 5 – vs. San Francisco 49ers

Result & Key Stats
The Los Angeles Rams fell 23–26 in a divisional heartbreaker despite a huge outing from QB Matthew Stafford, who threw for 389 yards and 3 touchdowns. WR Puka Nacua once again shined with 85 yards and a touchdown on 10 catches, while RB Kyren Williams contributed 66 yards and 2 scores through the air. Even with 467 total yards of offense, turnovers and missed opportunities kept Los Angeles from finishing the upset.

Key Moments & Injuries
The Rams clawed back into the game in the fourth quarter after Stafford engineered two quick touchdown drives, but their rally stalled when San Francisco’s defense tightened in the red zone. WR Davante Adams provided another strong showing with 88 yards, and WR Tutu Atwell stretched the defense with a 72-yard performance. Defensively, LB Nate Landman led all tacklers with 14 stops, and rookie DE Jared Verse flashed disruptive potential despite not recording a sack. However, the team suffered setbacks as TE Tyler Higbee (hip) and T Rob Havenstein (ankle) were listed as doubtful heading into Week 6, potentially weakening both the passing attack and protection.

Looking Ahead
The Rams will travel east to face the Baltimore Ravens in Week 6. Maintaining offensive rhythm will be critical, but the focus must shift toward cleaning up ball security and tightening the defense against Lamar Jackson’s dual-threat ability. If Stafford and his weapons continue producing at a high level, the Rams could turn this narrow loss into momentum heading into a tough road test.

Week 6 – vs. Baltimore Ravens

The Los Angeles Rams handled business on the road, beating Baltimore 17–3 at M&T Bank Stadium. Matthew Stafford was efficient (17/26, 181 yards, 1 TD), Kyren Williams ground out 50 yards with a short score, and TE Tyler Higbee caught the lone TD. WRs Puka Nacua and Jordan Whittington chipped in chain-moving grabs as L.A. balanced 181 passing yards with 74 on the ground.

Defensively, it was a statement. LB Nate Landman piled up 17 tackles, EDGE Byron Young notched 2.0 sacks, and rookie Jared Verse added another. S Quentin Lake grabbed a key interception, while DBs Kamren Kinchens and Kamalani “Kobe” Durant helped hold Baltimore to three points. Ball security remains a small concern after two Stafford fumbles, but the defense repeatedly bailed out the offense with four sacks and relentless pressure.

Looking Ahead: At 4–2, the Rams head into a marquee interconference test vs the Jacksonville Jaguars in Week 7. Keeping Stafford clean (Rob Havenstein, Tutu Atwell status to monitor) and leaning on Williams/Nacua efficiency will be pivotal, while the Young-Verse rush duo looks to disrupt Trevor Lawrence early and often.

Week 7 – vs. Jacksonville Jaguars

The Los Angeles Rams completely dominated the Jaguars 35–7, showcasing one of their most efficient performances of the season. QB Matthew Stafford threw five touchdown passes on just 182 yards, spreading the ball around to multiple targets. WR Davante Adams caught three of those scores, proving unstoppable in the red zone, while TE Theo Ferguson and rookie WR Kaden Mumpfield each added one touchdown reception.

Key Moments & Performances

The Rams’ offensive line kept Stafford clean all game, allowing zero sacks, while the defense completely overwhelmed Jacksonville with seven sacks led by Nick Landman (1.5), Byron Young (1.5), and rookie Jared Verse. Safety Quentin Lake and LB Kam Curl also shined in coverage, forcing bad throws and limiting big plays. LA’s defense allowed just 7 points and only one red-zone trip all afternoon.

Looking Ahead

Heading into their Week 8 bye, the Rams (5–2) have firmly reasserted themselves as contenders in the NFC West. With Puka Nacua and Rob Havenstein expected to recover from injuries after the break, LA will look to maintain its balanced attack when it returns to action in Week 9.

Odds to Win Division & Super Bowl

• Division Odds: +175
  
• Super Bowl Odds: +1800
  

Predictions

If Stafford stays healthy, the Rams will challenge the 49ers for the division. Projected finish: 10-7, 2nd place in NFC West, Wild Card contender.